I have an IPA and would like to upload it with Application Loader. But when I click "Open package" in Application Loader, I cannot select the IPA file, it is greyed out.
How can I upload this IPA file to iTunes Connect with Application Loader?
It is wrong to click the "Open package" button. Use "Deliver Your App" instead. For that feature to be available, online at itunesconnect.apple.com a new version must be created which accepts the wanted IPA.
Then the IPA can be uploaded, which is a ZIPped Application.
Specifically for iOS projects, you only need to submit a .app(generate by Xcode) which is zipped.
来源：https://stackoverflow.com/questions/12826481/upload-ipa-with-application-loader