Topic modelling, but with known topics?
问题 Okay, so usually topic models (such as LDA, pLSI, etc.) are used to infer topics that may be present in a set of documents, in an unsupervised fashion. I would like to know if anyone has any ideas as to how I can shoehorn my problem into an LDA framework, as there are very good tools available to solve LDA problems. For the sake of being thorough, I have the following pieces of information as input: A set of documents (segments of DNA from one organism, where each segment is a document) A