I doubt this is possible without extensive jail-breaking, but is it at all possible to edit the iPad's (or any iOS device's) hosts file? No. Apps can only modify files within the documents directory, within their own sandbox. This is for security, and ease of installing/uninstalling. So you could only do this on a jailbroken device. tremoloqui The previous answer is correct, but if the effect you are looking for is to redirect HTTP traffic for a domain to another IP there is a way. Since it technically is not answering your question, I have asked and answered the question here: How can I