Document base E:\web\.metadata\.plugins\org.eclipse.wst.server.core\tmp0\wtpwebapps\mysite does not exist or is not a readable directory

Question

Tomcat Version:6.0.53

Log: java.lang.IllegalArgumentException: Document base E:\\web.metadata.plugins\\org.eclipse.wst.server.core\\tmp0\\wtpwebapps\\mysite does not exis