How to disable keyboard shortcuts in Mac OS X?

Question

I would like to disable keyboard shortcuts Command-W and Command-Q in Mac OS X 10.8 Mountain Lion.

This is because they inter

Answer 1

A solution that may work for factory hotkeys in individual apps which conflict with your desired assignment:

Use the built-in hotkey management:

System Preferences | Keyboard | Shortcuts | App Shortcuts

...to map the pre-existing to some hard-to-hit keyboard combination (like Cmd-Opt-Shift-backslash). This will free-up the old key combination for assignment.