Compojure's what I used to build a tiny blogging application. It's modeled on Sinatra, which is a minimal, light-weight web framework for Ruby. I mostly just used the routing, which is just like Sinatra's. It looks like:
(GET "/post/:id/:slug"
(some-function-that-returns-html :id :slug))
There's no ORM or templating library, but it does have functions that turn vectors into HTML.