I have a VS2010 solution with couple of Qt-based projects. Every time when i modify files from one certain project, generated files (moc_*.cpp ones) changes its properties to be
There is a related question.
First you have to check the MocDirectory in the Qt Project Settings. Originally, I set it to the wrong value $(Configuration) and encountered the same problem as you.
After I changed it to $(ConfigurationName), the problem disappeared.
The reason that when the wrong value is set, MocDirectory points to the same directory for different project configuration (e.g. debug and release). When the project is built, it will excluded the generated files in MocDirectory with respect to other project configurations. Since all the configurations refer to the same MocDirectory, all generated files will be excluded.