I work on two different projects. One is an asp.net web project, the other an addin for an arcmap.exe. For debugging the addin the option \"Use Managed Compatibility Mode\"
The solution for now is without an extension. As described in Switching to Managed Compatibility Mode in Visual Studio 2013 it is possible to add a configuration in the .csproj file by hand:
<PropertyGroup>
<Configuration Condition=" '$(Configuration)' == '' ">Debug</Configuration>
...
<DebugEngines>{351668CC-8477-4fbf-BFE3-5F1006E4DB1F}</DebugEngines> <!-- add this line -->
...
</PropertyGroup>
This has to be done for the "Startup Project". After setting the property for the project, The option "Use Managed Compatibility Mode" can be unchecked in Settings - Debug.