I use clisp 2.48 (2009-07-28) on Mac OS X 10.6.4. I downloaded the clisp with \'sudo port install clisp\'.
After installing quick lisp, I installed some packages, a
I'm on 10.4, so I had to also install ffcall - I don't know if you installed it already. When installing clisp I added +dynffi to the end and it worked for me.
sudo port install ffcall sudo port install clisp +dynffi