Not able to set breakpoint in visual studio

Question

I am using Visual Studio 2013 and I am facing a weird issue from last few days. Whenever I try to set a break point, I get an error

\"The Following breakpoint can         


        

Answer 1

In my case, this was caused by a faulty merge of the .csproj contents, to be specific a ItemGroup contained a node which belonged in its own ItemGroup.

Answer 2

I used a MVC project and couldn't set any Breakpoints in the Razor-View.
All my projects were build in Debug-mode and a clean+rebuild didn't help either.
I had to remove this entry:

<configuration>
    <appSettings>
        <add key="Microsoft.VisualStudio.Enterprise.AspNetHelper.VsInstrLocation" value="C:\Program Files (x86)\Microsoft Visual Studio 14.0\Team Tools\Performance Tools\vsinstr.exe"/>
    </appSettings>
</configuration>

in the Web.config and breakpoints worked again.

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I found a related thread: Visual Studio 2013/2015 profiler adds Not publishable lines in web.config? Seems to be a Bug