I\'m just putting this one out there since its a Google Zero-resulter which means I win a prize?
Cannot start IIS Express 7.5 after reinstall from one account, but I
Only Deleting config folder did not work for me. Also i did this
"Delete the following file <>.vs\config\applicationhost.config, the .vs folder may be hidden"
https://social.msdn.microsoft.com/Forums/en-US/1a25b14d-02e5-4adc-bd79-4d215893fed2/vs-2013-unable-to-start-program-cprogram-files-x86iis-expressiisexpressexe?forum=visualstudiogeneral
Also, you might need to change the line
applicationDefaults applicationPool="Clr4IntegratedAppPool"
to
applicationDefaults applicationPool="Clr2IntegratedAppPool"
in the file...
C:\users\jmitchell\My Documents\IISExpress\config\applicationhost.config
if you continue to get the same error (as I did) after following the instructions on the post above. The issue being solved here is that you don't have .NET4 installed, and so are reverting to using .NET2
Thanks