I realise that there are many older questions addressing the general question of NUnit v MSTest for versions of Visual Studio up to 2008 (such as this one).
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MSUnit runs your test cases under conditions that are different from the actual execution environment. Specifically, the deployed files differ from those that are deployed when you run your actual project. Nethertheless, there is the [DeploymentItem]-Attribute to specify which files shall be deployed by MSUnit. So if your application depends on any external files, such as
then MSUnit is not the right choice, because the MSUnit tests never cover what your file system is going to look like in execution environment. The Visual Studio Project File settings for deploying files (Copy always, Content, etc.) are ignored by the MSUnit runner. So those settings cannot be tested.
I've mainly used NUnit, some xUnit and some MSTest. They seem functionality equivalent, but I don't like the MSTest test runner. It runs in visual studio so it either crowds the screen or is on another monitor getting in the way everytime I tab to visual studio. (I run NUnit on another monitor, but it doesn't cover everything on that monitor everytime I focus visual studio). It takes too many clicks to find out what test failed and why.
NUnit can run in the background until a test fails, at which point it shows you information about the breaking test. This seems like the ideal for keeping red/green/refactor going smoothly.
Nope. Same issues regarding appdomains and assembly resolving still exist. I would avoid unless you want the new goodness for other functional testing or integration with Team System.
One major difference between the two is that MSTest makes a copy of the current DLLs every time it runs a test. If you're doing TDD and running your tests frequently, this can eat up a lot of hard drive space.
If you're using MSTest, you can change this setting in Tools > Options > Test Tools > Test Execution. "Limit number of old Test Results to" is set to 25 by default in Visual Studio 2010. I usually change it to 1.
To correct some old information on the thread;
If you think you'll ever run your tests in 64 bit mode, use NUnit. MsTest is only x86.