I solved this issue. It's working fine now.
I'm using:
+ Window 10
+ VirtualBox-5.0.2-102096-Win
+ Genymotion-2.5.3
Step 1: We should set Run as this program as an administrator & Compatibility mode Windows 8 for those file.
C:\Program Files\Oracle\VirtualBox
+ VBoxHeadless.exe
+ VBoxManage.exe
+ VirtualBox.exe
C:\Program Files\Genymobile\Genymotion
+ genymotion.exe
Step 2: My Computer -> Manage-> Device Manager-> Network adapters
Remove all items with name: VirtualBox Host-Only Ethenet Adapter #...
Step 3: Open Virtual Box and go to File -> Preferences -> Network -> Host Only Networks
Remove all and create new host with information:
Adapter Tab:
IPv4 Address: 192.168.1.201
IPv4 Network Mask: 255.255.255.0
DHCP Server Tab:
Server Address: 192.168.1.100
Server Mask: 255.255.255.0
Lower Address Bound: 192.168.1.101
Upper Address Bound: 192.168.1.199
Step 4: Run Genymotion again. It's will work.
> Screenshots