I have a current project running using APE that needs to work on C#/.NET... I was wondering if anyone had any suggestions for either a method of approaching Reverse AJAX/Com
I think that you asking for something like
http://www.frozenmountain.com/websync/
or
http://www.aaronlerch.com/blog/2007/07/08/creating-comet-applications-with-aspnet/
This is called comet technique and is a web application model in which a long-held HTTP request allows a web server to push data to a browser, without the browser explicitly requesting it.
PokeIn comet ajax library works platform independent. ( Mono + .Net )