I am building an application with a REST-based API and have come to the point where I am specifying status codes for each requests.
What status code should i send for
You should definitely give a more detailed explanation in the response headers and/or body (e.g. with a custom header - X-Status-Reason: Validation failed
).
For input validation failure: 400 Bad Request + your optional description. This is suggested in the book "RESTful Web Services". For double submit: 409 Conflict
Update June 2014
The relevant specification used to be RFC2616, which gave the use of 400 (Bad Request) rather narrowly as
The request could not be understood by the server due to malformed syntax
So it might have been argued that it was inappropriate for semantic errors. But not any more; since June 2014 the relevant standard RFC 7231, which supersedes the previous RFC2616, gives the use of 400 (Bad Request) more broadly as
the server cannot or will not process the request due to something that is perceived to be a client error
Which means this response is sent when the web server, after performing server-driven content negotiation, doesn't find any content that conforms to the criteria given by the user agent.