Could not load file or assembly or one of its dependencies. Access is denied. The issue is random, but after it happens once, it continues

Question

I have found plenty of information out there about this error: \'ERROR: Could not load file or assembly \'*.dll\' or one of its dependencies. Access is denied.’ But i haven

Answer 1

Go to IIS -> Application Pool -> Advance Settings -> Enable 32-bit Applications

Answer 2

In my case it was due to the Access Protection feature of my anti-virus (McAfee). It was obviously blocking access to this file, as of such the error.

I disabled it and the solution ran. You might want to check any utility application you might have running that could be affecting access to some files.

Answer 3

I got this error running from VS. Turned out I'd opened a solution without running Visual Studio as admin. Closing Visual studio down and running it again as admin then rebuilding solved this for me.

Hope that helps someone.

Answer 4

If you still facing the issue try this:

Open your IIS Manager -> Application Pools -> select your app pool -> Advance Setting -> Under 'Process Model' set 'Load User Profile' setting as True

Answer 5

I had the same issue, fixed by rebuild and redeploy ALL Dependents Dll files

Answer 6

For me, the following hack worked; Go to IIS -> Application Pools -> Advance Settings -> Process Model -> Identity Changed from Built-in Account (ApplicationPoolIdentity) to Custom Account (My Domain User)