I need to send hundreds of newsletters, but would like to check first if email exists on server. It\'s called SMTP validation, at least I think so, based on my research on I
Don't take this the wrong way, but sending newsletters to more than a handful of people these days is a fairly serious matter. Yes, you need to be monitoring bounces (rejected emails) which can occur synchronously during the SMTP send (typically if the SMTP server you are connected to is authoritative), or asynchronously as a system-generated email message that occurs some amount of time after the SMTP send succeeded.
Also keep the CAN-SPAM Act in mind and abide by the law when sending these emails; you've got to provide an unsub link as well as a physical street address (to both identify you and t0 allow users to send unsub requests via snail-mail if they so choose).
Failure to do these things could get your IP null-routed at best and sued at worst.