I\'m starting a web application that will target Mobile Safari on iPhone/iPod Touch. I\'m evaluating the available client-side JavaScript/CSS libraries/frameworks that are
I would second jQTouch. It uses native CSS animations and behaves reasonably smoothly on my iPod Touch.
PhoneGap isn't exactly what you're asking about, but is something you might want to be aware of. It's a wrapper for making iPhone apps using HTML/CSS/JavaScript.
The folks at DHTMLX also have a mobile library
DEMOS: http://dhtmlx.com/touch/samples/
QuickConnectiPhone has what you are asking for. There is a custom project type for Dashcode that allows you to quickly create your app. If you then want to run it installed on an iPhone or touch you can then drop it into Xcode and compile it up.
It includes wrappers for AJAX and the SQLite database that exists within the Safari browser on the iPhone and touch.
You can get it at
http://sourceforge.net/projects/quickconnect/
More information is available at
http://tetontech.wordpress.com
JQTouch is not really an app dev framework..it is a style and animation "wrapper".
QuickConnect provides start to finish app development on iphone, droid, and blackberry. The iphone is the most complete.
It can incorporate JQTouch for look and feel and is well-documented.
PhoneGap can be used in conjunction with JQTouch as well but in my experience PG documentation and instruction is harder to find.