Idea of having time restricted license and check for it in locally installed program will not work. Even with perfect obfuscation, license check can be removed. However if you check license on remote system and run significant part of the program on your closed remote system, you will be able to protect your IP.
Preventing competitors from using the source code as their own or write their inspired version of the same code, one way to protect is to add signatures to your program logic (some secrets to be able to prove that code was stolen from you) and obfuscate the python source code so, it's hard to read and utilize.
Good obfuscation adds basically the same protection to your code, that compiling it to executable (and stripping binary) does. Figuring out how obfuscated complex code works might be even harder than actually writing your own implementation.
This will not help preventing hacking of your program. Even with obfuscation code license stuff will be cracked and program may be modified to have slightly different behaviour (in the same way that compiling code to binary does not help protection of native programs).
In addition to symbol obfuscation might be good idea to unrefactor the code, which makes everything even more confusing if e.g. call graphs points to many different places even if actually those different places does eventually the same thing.
Logical signature inside obfuscated code (e.g. you may create table of values which are used by program logic, but also used as signature), which can be used to determine that code is originated from you. If someone decides to use your obfuscated code module as part of their own product (even after reobfuscating it to make it seem different) you can show, that code is stolen with your secret signature.
