This block is the most important for me:
(setq locale-coding-system 'utf-8)
(set-terminal-coding-system 'utf-8)
(set-keyboard-coding-system 'utf-8)
(set-selection-coding-system 'utf-8)
(prefer-coding-system 'utf-8)
I've never been clear on the difference between those, though. Cargo cult, I guess...