You can also use Microsoft's own Expression Web SuperPreview
Download page: http://www.microsoft.com/downloads/details.aspx?FamilyID=8e6ac106-525d-45d0-84db-dccff3fae677&displaylang=en
Further info: http://expression.microsoft.com/en-us/dd565874.aspx
Edit:
Sorry I didn't notice your "...and debug it..." statement in the original post. I think SuperPreview will just show a side-by-side visual comparison. If you need to debug javascript or anything like that, then I would use the virtualization methods mentioned above. (In practice I actually use virtualization for testing, but I figured I'd suggest something different.)