This question probably looks a lot like IDE for ironpython on windows question here on stackoverflow. But I read the answers on that question I still have no idea what IDE I sh
Most of the time I use Scite for my IronPython scripting -- since I'm normally using it as a scripting language for build process rather than anything else, one page of syntax highlighting is usually enough.
As a general purpose Python IDE I use NetBeans Python EA, which treats CPython, Jython and IronPython pretty much as equals, so I can just set it to the platform I want to use today, and everything else remains the same.
Michael Foord has compared different IDEs for IronPython. You can find it here.
You now have a good Visual studio 2010 integration with IronPython Tools.