Take a look at Quickbooks SDK and Documentation. The SDK has two COM interface: QBFC and QBXML. The difference in using QBXML, you need to serialize and deserialize XML manually which isn't hard once you get the handle of it. And I find QBXML much more convenient since you can choose to include requests and responses you need.
Also, if you plan to use Quickbooks SDK, the Online Reference is your best friend.