No, it's not the only best way to do things.
MVC is just a design pattern. The goal of all design patterns is simplicity. So as long as it makes your design simpler, go with it. If it makes things more complex for your specific application, try a different approach.
Unfortunately, some people think if they see a pattern, they should use it. It's just not true. Design patterns don't inherently make your application better. They are not an end. They are a means to an end (which is simplicity). So you should use them only if they are worth it.
In my opinion, over-architecting things without a good reason is worse than writing code without any specific design.
EDIT: Regarding ASP.NET MVC: I have a negative personal bias toward ASP.NET Web forms. Before MVC, I did most of the dynamic aspects of advanced projects by writing custom handlers to have fine grained control over the HTML. Web Forms make Web development very easy but they have particularly a couple things that are good but sometimes are problematic. The first of which is ViewState and the second is complex WebControl architecture. Don't get me wrong. Those are signs of brilliance of ASP.NET. I haven't seen a single platform for Web development as easy as ASP.NET Web Forms and this is only because of great WebControl support which requires ViewState. However, in some projects, you want to have precise control on rendered HTML (specially when you have some client-side logic). You also want to make server side code maintainable in large projects. In those areas, ASP.NET MVC really shines. But I think ASP.NET Web Forms will remain a great technology where it's more applicable. After all, as I said regarding design patterns in general, you should carefully evaluate your design to see which one better fits your needs.
Specifically, about data access, MVC usually requires more code than Web Forms counterparts. For presenting tabular data (i.e where GridView is applicable), I think ASP.NET Web Forms is the easier way to accomplish things. However, most data driven Web apps are not just manipulating a table directly in a database. They have complex layout. StackOverflow is a great example of this. It is certainly data driven, but ASP.NET MVC better suits it.
