Visual Studio 2010 debug not starting, F5 or click on “Play” not working, not doing anything. Waiting 2-3 minutes solves the issue

Question

I have a relatively simple C# (Framework 4) console application. When I click the \"Play\" icon or hit F5 (i.e. start the program in debug mode), the icon becomes gra

Answer 1

Check the Project Properties in the Compile tab, select the Advanced Compile Options.

If you are targeting the .NET Framework 4 Client Profile, you cannot reference an assembly that is not in the .NET Framework 4 Client Profile.

More information about the .Net Framework 4 Client Profile here