I have a relatively simple C# (Framework 4) console application. When I click the \"Play\" icon or hit F5 (i.e. start the program in debug mode), the icon becomes gra
I had a problem like this. I was having problems using "run" when the network was involved.
I moved all of the files related to the program/solution to my local hard-drive (C:); they were on a network drive. Be sure to check the "References" (Look under the "Project" pull-down for the properties; then look for "References").
I would make sure all references are on you local hard-drive and set the "Path" correctly (to the reference on you local hard-drive) in the References tab. This seemed to fix the issue.