I have been playing with the Ruby library \"shoes\". Basically you can write a GUI application in the following way:
Shoes.app do
t = para \"Not clicked!\"
b
With some Metaclass magic to keep the ordering I have the following working. I'm not sure how pythonic it is but it is good fun for creating simple things.
class w(Wndw):
title='Hello World'
class txt(Txt): # either a new class
text='Insert name here'
lbl=Lbl(text='Hello') # or an instance
class greet(Bbt):
text='Greet'
def click(self): #on_click method
self.frame.lbl.text='Hello %s.'%self.frame.txt.text
app=w()