In a SharePoint list I want an auto number column that as I add to the list gets incremented. How best can I go about this?
So I am not sure I can really think of why you would actually need a "site collection unique" id, so maybe you can comment and let us know what is actually trying to be accomplished here...
Either way, all items have a UniqueID property that is a GUID if you really need it: http://msdn.microsoft.com/en-us/library/microsoft.sharepoint.splistitem.uniqueid.aspx