I have a cron script that executes a PHP script every 10 minutes. The script checks a queue and processes the data in the queue. Sometimes the queue has enough data to last ov
If you need it to be absolutely crash-proof, you should use semaphores, which are released automatically when php ends the specific request handling.
A simpler approach would be to create a DB record or a file at the beginning of the execution, and remove it at the end. You could always check the "age" of that record/file, and if it's older than say 3 times the normal script execution, suppose it crashed and remove it.
There's no "silver bullet", it just depends on your needs.