Here\'s my environment: IIS7.5 on Win 7, .NET 4, App Pool Integrated
web.config
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Please note that this is same as Stackoverflow post --> ManagedPipelineHandler for an AJAX POST crashes if an IE9 user navigates away from a page while that call was in progress.
This appears to be a regression in ASP.NET 4.5. ASP.NET team is working on a patch, but there is a temporary workaround (see the post referred above).
If you cannot wait for public broad update, you can contact Microsoft customer support for hotfix requests. Just follow the regular process of opening a support case. For example, file online https://support.microsoft.com/oas/default.aspx?&gprid=548&&st=1&wfxredirect=1&sd=gn or call support http://support.microsoft.com/default.aspx?id=fh;en-us;offerprophone. You may need to pay minimal amount upfront but you may get refund based on customer support policies. Just ask customer support professional to contact netfx45compat at Microsoft dot com to get quick context on this issue.
Thanks Varun Gupta (.NET Framework Compatibility)