Is it possible to differentiate between 0 and -0?

Question

I know that the integer values 0 and -0 are essentially the same. But, I am wondering if it is possible to differentiate between them.

For exam

Answer 1

Let's begin with representing 0 in 2's complement (of course there exist many other systems and representations, here I'm referring this specific one), assuming 8-bit, zero is:

0000 0000

Now let's flip all the bits and add 1 to get the 2's complement:

1111 1111 (flip)
0000 0001 (add one)
---------
0000 0000

we got 0000 0000, and that's the representation of -0 as well.

But note that in 1's complement, signed 0 is 0000 0000, but -0 is 1111 1111.