The following two diagrams are my understanding on how threads work in a event-driven web server (like Node.js + JavaScript) compared to a non-event driven web server (like IIS
Node may use threads for IO. The JS code runs in a single thread, but all the IO requests are running in parallel threads. If you want some JS code to run in parallel threads, use thread-a-gogo or some other packages out there which mitigate that behaviour.
Same as 1.
, threads are created by Node for IO operations.
You don't have to handle threading, unless you want to. Easier to develop. At least that's my point of view.
A node application can be coded to run like another web server. Typically, JS code runs in a single thread, but there are ways to make it behave differently.
Personally, I recommend threads-a-gogo (the package name isn't that revealing, but it is easy to use) if you want to experiment with threads. It's faster. Node also supports multiple processes, you may run a completely separate process if you also want to try that out.