\"Fluent interfaces\" is a fairly hot topic these days. C# 3.0 has some nice features (particularly extension methods) that help you make them.
FYI, a fluent API means
As @John Sheehan mentioned, Ninject uses this type of API to specify bindings. Here are some example code from their user guide:
Bind().To(); Bind().ToSelf(); Bind().ToSelf().Using();