Filemaker is enormously powerful and versatile. Excellent multi-user support. You can create wonderful solutions in Filemaker with document management, web interface, iphone interface, automated publishing support, scheduled scripts, PDF/Excel/HTML reports, XML support, caller ID record lookup, integration of web data (UPS & Fedex linked to order record for example). Extensible with plugins. It's like being in the Home Depot of data. Don't try to build Amazon; other than that what can't you build with it, and faster app dev than most anywhere else?