A Real-Time R package would be my choice, using C Streaming perhaps.
Also I'd like a more robust web development package. Nothing as extensive as Ruby on Rails but something a bit better than Sweave combined with R2HTML, that can run on RApache. I think this needs to be a huge area of emphasis for R in general.
I realize LaTeX is better markup for certain academia but in general I think HTML should be the markup language of choice. More needs to be done in terms of R Web Apps, so applications can be hosted on huge RAM remotely and R can start being used for SaaS data applications and other graphics choices.