I\'m working on a web app that is somewhere between an email service and a social network. I feel it has the potential to grow really big in the future, so I\'m concerned about
If your data is this easy to shard, why not just use a standard database engine, and if you scale large enough that the DB becomes the bottleneck, shard the database, with different users in different instances? The effect is the same, but you're not using scores of tiny little databases.
In reality, you probably have at least some shared data that doesn't belong to any single user, and you probably frequently need to access data for more than one user. This will cause problems with either system, though.