Off my head ...
Pinax has a profile for a social networking site.
Convore and Disqus uses Django for some parts of their websites.
About Django scalability - Does Django Scale ?
Edit: Found this while I was googling for something else.
PyCon 2011: Django: Pitfalls I Encountered and How to Avoid Them
Presented by Luke Sneeringer
Are you starting a moderate to large
sized Django project? Do you need to
plan ahead and build an application
that will react to unanticipated
needs? This talk covers some
techniques and pitfalls I encountered
in writing my first reasonably large
Django site, and what I did
differently the second time I started
a project.
