I need to generate a diff for a single file that will show the differences between two versions, which are actually tags in github. I then want to send this diff to someone via
GitHub only exposes the way to show diff between two commits.
Provided those tags actually point to commits, the Url format would be something like
https://github.com/{user}/{repository}/compare/{from-tag}...{until-tag}
As an example, https://github.com/libgit2/libgit2sharp/compare/v0.9.0...v0.9.5 shows the diff between two versions of the LibGit2Sharp project. This diff includes all the modified files.
If you want to retrieve an url that targets a specific file:
For instance, given the diff above, the link https://github.com/libgit2/libgit2sharp/compare/v0.9.0...v0.9.5#diff-11 will point to the LazyFixtures.cs
changes that occured between version v0.9.0 and v0.9.5.
Following your comment which states that your diff is too big to be rendered through the Web interface, how about reverting to good old command line tooling? You could redirect the output of the diff to a file and then send the file as an email attachment.
$ git diff v0.9.0 v0.9.5 -- LibGit2Sharp.Tests/LazyFixture.cs > /tmp/lazyfixture.diff