We are using it with our website that teachers Chinese, www.dominochinese.com. Our host is pythonanywhere.com and we love the simplicity of it. I work on building stuff instead of wishing I could get stuff working. I worked with django for 1.5 years and I hated it. In a sense I feel web2py is the PHP but in python. It makes people quickly do stuff without going into object oriented programming, which can be really confusing for beginners to intermediate programmers.
