1) As others have said, C does less for you. No initializing variables, no array bounds checking, no memory management, etc. Those features in other languages cost memory and CPU cycles that C doesn't spend.
2) Answers saying that C is less abstracted and therefore faster are only half correct I think. Technically speaking, if you had a "sufficiently advanced compiler" for language X, then language X could approach or equal the speed of C. The difference with C is that since it maps so obviously (if you've taken an architecture course) and directly to assembly language that even a naive compiler can do a decent job. For something like Python, you need a very advanced compiler to predict the probable types of objects and generate machine code on the fly -- C's semantics are simple enough that a simple compiler can do well.
