Is there a good shortcut for modifying python variables using methods?

Question

i += 1 can be used instead of i = i + 1.

Is there a similar shorthand for string = string.replace(...)?

Answer 1

No, because there is no built-in syntax for this.

For a string, you can still use +=:

>>> x = "hello"
>>> x += " world"
>>> x
'hello world'

Because += is defined for strings. There just isn't an assignment operator for replace.