In two-complement arithmetic to get a reverse number (for example for value 16 to get value -16) you need reverse each bit and add 1.
In your example, to get -16 from 16 that is represented as
00000000000000000000000000010000
you need reverse each bit. You will get
11111111111111111111111111101111
Now you must add 1 and you will get
11111111111111111111111111110000
As you can see if you add these two values, you will get 0. It proves that you did all correctly.