how to determinate destination MAC address

Question

My application is running on CentOS 5.5 I need to send raw packets using libpcap API:

pcap_inject() or pcap_sendpacket()

To the specific IP add

Answer 1

In general, MAC addresses don't matter for remote targets. They are not routable; a router here at my office doesn't know the MAC addresses of network cards across the Internet. That's what IP addresses are for. Do you mean local only?