I have a list and pandas dataframe data that looks like this:
user_id = [10, 15, 20, 25, 30, 32, 40, 45, 50] user_id value 10 45 20 49 25
You can just use Series.isin() with negation (~).
~
df[~df["user_id"].isin(set(user_id))]
Conversion to set is always preferable as you'll better running time.