I want to use Microsoft.Office.Interop.Excel to pull some data out of an XLS file. I have Visual Studio 2010 and the Office Developer Tools installed. However, I am getting a
Microsoft Office Starter 2010 cannot run Office solutions that you create by using Visual Studio 2010. http://msdn.microsoft.com/en-us/library/bb608617.aspx
So I'd say the answer to your questions is yes. Now I realise you probably solved it already. But just in case anyone else runs into this issue. :-)