OK, so far I\'ve uninstalled & re installed Office-2010 3 to 4 times, done hours of research for 3 days with no success. I started getting this error either from Vbscript or
Putting an answer here for others like myself who have this issue and the normal solutions don't work.
Another potential cause of this is corrupted temporary files. I think it may only apply if the file you are trying to open is on a network drive or other remote host.
Anyway, try wiping your temp folder (as in the one you get to if you type %temp%
into Windows Explorer) then restarting the computer.