This is my sample file
#%cty_id1,#%ccy_id2,#%cty_src,#%cty_cd3,#%cty_nm4,#%cty_reg5,#%cty_natnl6,#%cty_bus7,#%cty_data8
690,ALL2,,AL,ALBALODMNIA,,,,
90,ALL2,,
Coming to the party late with a VBA based approach. An alternative way to regex is to to parse the file and remove a comma when the 4th field is empty. Using microsoft scripting runtime this can be acheived the code opens a the file then reads each line, copying it to a new temporary file. If the 4 element is empty, if it is it writes a line with the extra comma removed. The cleaned data is then copied to the origonal file and the temporary file is deleted. It seems a bit of a long way round, but it when I tested it on a file of 14000 rows based on your sample it took under 2 seconds to complete.
Sub Remove4thFieldIfEmpty()
Const iNUMBER_OF_FIELDS As Integer = 9
Dim str As String
Dim fileHandleInput As Scripting.TextStream
Dim fileHandleCleaned As Scripting.TextStream
Dim fsoObject As Scripting.FileSystemObject
Dim sPath As String
Dim sFilenameCleaned As String
Dim sFilenameInput As String
Dim vFields As Variant
Dim iCounter As Integer
Dim sNewString As String
sFilenameInput = "Regex.CSV"
sFilenameCleaned = "Cleaned.CSV"
Set fsoObject = New FileSystemObject
sPath = ThisWorkbook.Path & "\"
Set fileHandleInput = fsoObject.OpenTextFile(sPath & sFilenameInput)
If fsoObject.FileExists(sPath & sFilenameCleaned) Then
Set fileHandleCleaned = fsoObject.OpenTextFile(sPath & sFilenameCleaned, ForWriting)
Else
Set fileHandleCleaned = fsoObject.CreateTextFile((sPath & sFilenameCleaned), True)
End If
Do While Not fileHandleInput.AtEndOfStream
str = fileHandleInput.ReadLine
vFields = Split(str, ",")
If vFields(3) = "" Then
sNewString = vFields(0)
For iCounter = 1 To UBound(vFields)
If iCounter <> 3 Then sNewString = sNewString & "," & vFields(iCounter)
Next iCounter
str = sNewString
End If
fileHandleCleaned.WriteLine (str)
Loop
fileHandleInput.Close
fileHandleCleaned.Close
Set fileHandleInput = fsoObject.OpenTextFile(sPath & sFilenameInput, ForWriting)
Set fileHandleCleaned = fsoObject.OpenTextFile(sPath & sFilenameCleaned)
Do While Not fileHandleCleaned.AtEndOfStream
fileHandleInput.WriteLine (fileHandleCleaned.ReadLine)
Loop
fileHandleInput.Close
fileHandleCleaned.Close
Set fileHandleCleaned = Nothing
Set fileHandleInput = Nothing
KillFile (sPath & sFilenameCleaned)
Set fsoObject = Nothing
End Sub