Boa Constructor is a classic RAD IDE for GUI applications (wxpython, both linux and windows). People is still using it but seems that development stopped some years ago. PythonCard is another RAD IDE I used in the past but also unmaintained right now
Although they are not IDEs, some tools are very helpful for GUI design like:
- wxglade (wxpython, included as a pluging in Stani Python Editor, only python2.x)
- qtdesigner (qt-pyqt or pyside, included in pyqt. Spyder IDE, build on pyqt, has a dedicated link to it. Works also for python 3.x)