How to reverse the y-axis of the imported image in Tkinter?

Question

For duplicate-markers: I am fully aware that there are some similar questions in matplotlib, such as this one. My question is about

Answer 1

An angle can be used like such:

image = Image.open("lena.jpg")
angle = 180
tkimage = ImageTk.PhotoImage(image.rotate(angle))
...

It would be possible to draw the picture, and use reversed coordinates (so when you know the size of the canvas, instead of saying 50x50, you could use (max-50)x(max-50).

The question is whether axes.imshow can handle the ImageTk.PhotoImage. Then again, I am not entirely sure if you'd just want this on a Tkinter canvas instead, e.g.:

canvas_obj = self.canvas.create_image(250, 250, image=tkimage)