Following the DroneKit instructions, I was able to run the hello.py code from their QuickStart guide: http://python.dronekit.io/guide/quick_start.html.
Fin, it looks like pySerial 3.0 was released in the past week which changes its API. pymavlink (used by DroneKit-Python) requires pySerial 2.0. I've filed an issue and will work to resolve it.
In the meantime, try pip install "pySerial>=2.0,<=2.9999" and see if this resolves your problem.